Assessment of the rapid test based on an immunochromatography technique for detecting anti-Treponema pallidum antibodies

Assessment of the rapid test based on an immunochromatography technique for detecting anti-Treponema pallidum antibodies.

A rapid test based on an immunochromatography assay - Determine Syphilis TP (Abbott Lab.) for detecting specific antibodies to Treponema pallidum was evaluated against serum samples from patients with clinical, epidemiological and serological diagnosis of syphilis, patients with sexually transmitted disease other than syphilis, and individuals with negative serology for syphilis. The Determine ...

Latex agglutination test for detecting antibodies to Treponema pallidum.

We have developed an automated latex agglutination test for Treponema pallidum (TPLA) for measurement of the concentration of treponemal antibodies in syphilitic sera. The assay needs neither a complicated pretreatment of the sera nor special techniques. Intra- and interassay precision studies showed high reproducibility. Potentially interfering substances, such as bilirubin, hemoglobin, trigly...

Comparison of Micro Neutralization Test with Hemadsorption-Inhibition Test, and Immunoflrorescence Technique for Detecting Mumps Antibodies

Preliminary evaluation of an immunochromatographic strip test for specific Treponema pallidum antibodies.

We evaluated a prototype immunochromatographic strip (ICS) test for qualitative detection of Treponema pallidum antibodies in 353 sera from 157 patients. For sera from 43 syphilis patients, the ICSs were reactive, while for sera from 114 patients without syphilis, including 22 with biologically false-positive Rapid Plasma Reagin test results, the ICSs were nonreactive. The ICS test may expand t...

Appraisal of the Treponema pallidum haemagglutination test.

Several attempts have been made to use haemagglutination reactions for the diagnosis of syphilis between 1932 and 1958. The first reliable method was developed by Rathlev (1965). Further results of investigations with this method have been reported by authors from Japan and from the Venereal Disease Research Laboratory in Atlanta, U.S.A. Rathlev prepared the reagents for the test in the Statens...